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Image Search Results
Journal: Journal of Enzyme Inhibition and Medicinal Chemistry
Article Title: Novel alloxazine analogues: design, synthesis, and antitumour efficacy enhanced by kinase screening, molecular docking, and ADME studies
doi: 10.1080/14756366.2024.2398551
Figure Lengend Snippet: Correlation between the binding free energy (Δ G b ) and IC 50 (µg.mL −1 ) of 8-methyl-2-methylthio-4-oxo-alloxazine-5-oxide (9e) , 2-(substituted amino) alloxazines (10a,c,f–i,l,n,q) , 3-alkyl-2-deoxo-2-methylthio-alloxazin-5-oxides (12c–e) , and 7-methoxy-4-oxo-3,4-dihydro-alloxazine-5-oxide (16c) against human oral epidermoid carcinoma cell line (KB).
Article Snippet: Two human tumour cell lines, CCRF-HSB-2 (human T-cell acute lymphoblastoid leukaemia) and
Techniques: Binding Assay